Team creates HIV therapy that lasts 2 weeks in exam model

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Research co-led by University of Washington pharmacy and medicine investigators has yielded a seven-day therapy for HIV. The therapy was successful in a macaque model.

The findings were published in a Mar emanate of a biography AIDS. Professors Rodney JY Ho of the School of Pharmacy and Ann Collier of a School of Medicine were lead authors; initial author was Jake Craft of a UW Department of Pharmaceutics.

The “Targeted Long-Acting Combination Antiretroviral Therapy” (TLC-ART) group combined three HIV drugs: tenofovir, lopinavir and ritonavir. The scientists hoped that doing so would overcome drug ineptitude in lymph nodes. The drug cocktail, given to 4 macaques, had determined levels lasting some-more than dual weeks, a conspicuous breakthrough. Currently HIV patients take mixed pills daily, that can poise challenges.

Other researchers on a group were Lisa McConnachie, Josefin Koehn, Loren Kinman, Carol Collins and Danny Shenare. The group is pursuing innovative treatments to overcome stipulations of stream verbal drug therapies.

Source: University of Washington

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